Genomics, Bioinformatics, and Computational Biology

Faculty
 

Identifying design principles of eukaryotic enhancers using embryonic gene expression in Drosophila
 
Buell, Robin
Sequencing, annotation, and comparative analyses of plant and plant pathogens genomes
 
The architecture of regulatory networks evolved to take advantage of stochastic fluctuations at the molecular level to generate advantageous phenotype distributions in bacterial populations
 
Computational and experimental methods for selective control of apoptosis signaling
 
Protein structure prediction and refinement based on evolutionary information
 
Statistical genetics, methodology and algorithm; Computational methods for microarray, genotyping, and identification of regulatory motifs
 
Functional characterization of genes that are predicted to encode Fe(II)/alpha-ketoglutarate -dependent hydroxylases or flavoenzmes
 
The contribution of transposable elements to genome evolution
 
Liu, Kevin J.
Development of new computational methodologies to analyze large-scale comparative genomic data in the context of complex evolutionary processes
 
Developmental epigenetics, embryonic development, and embryonic stem (ES) cells; ChIP-chip and RNA
 
Genome-wide identification of transcription factor binding sites and sigma factor function in bacteria that undergo development
 
Protein structure and flexibility modeling, and high-throughput structure-based screening for inhibitor discovery
 
Functional genomics in evolving microbial and digital systems
 
RNAi & Proteomic Approaches for Quantitative Analysis of Molecular Pathways (kinases & phosphatases)
 
Bayes and Empirical Bayes methods to analyze microarray data
 
Genomic plasticity in Ralstonia pickettii and JGI sequencing two isolates
 
Precision medicine, specifically personalized medicine by assessment of multiple omics during longitudinal profiling. Creation of tools for multi-omics integration and generation of omics datasets for systems level analyses.
 
Optimal Control Theory and Non-equilibrium Statistical Mechanics of Regulatory Gene Networks
 
Search algorithms for Genome Sequence databases and profile Hidden Markov Models
 
Electronic nanocomponents in Geobacter biofilms
 
Metagenomics of microbial communities
 
Bioinformatics and comparative genomics. Gene family and cis-regulatory evolution
 
Statistical genetics and genomics. Experimental designs and statistical models to uncover the genetics basis of phenotypic and transcriptomic variation in animal species
 
Similarity search in large-scale database; protein homology classification; ncRNA identification
 
Proper analysis of efficient microarray experiments based on mixed effects models
 
Molecular phylogenetics and comparative chloroplast genomics in euglenophytes